Cloned (Comment) | Organism |
---|---|
expression of SLS-GFP fusion protein in Catharanthus roseus cells show localization to the endoplasmic reticulum membranes | Catharanthus roseus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | the enzyme is anchored to the endoplasmic reticulum via a N-teminal helix, thus allowing the production of secologanin on the cytosolic side of the endoplasmic reticulum membrane | Catharanthus roseus | 5783 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
loganin + [reduced NADPH-hemoprotein reductase] + O2 | Catharanthus roseus | - |
secologanin + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Catharanthus roseus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epidermis | epidermis-specific expression of SLS | Catharanthus roseus | - |
leaf | - |
Catharanthus roseus | - |
additional information | RT-PCR tissue expression analysis, overview | Catharanthus roseus | - |
seedling | - |
Catharanthus roseus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
loganin + [reduced NADPH-hemoprotein reductase] + O2 | - |
Catharanthus roseus | secologanin + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CYP71A1 | - |
Catharanthus roseus |
cytochrome P450 secologanin synthase | - |
Catharanthus roseus |
SLS | - |
Catharanthus roseus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome P450 | CYP71A1 | Catharanthus roseus |
General Information | Comment | Organism |
---|---|---|
malfunction | mutant DELTAthSLS fusion protein forms punctuated aggregates in the cytosol in close vicinity with plastids | Catharanthus roseus |
metabolism | the enzyme catalyzes the last step of the monoterpene secoiridoid pathway | Catharanthus roseus |
additional information | the enzyme is anchored to the endoplasmic reticulum via a N-teminal helix, thus allowing the production of secologanin on the cytosolic side of the endoplasmic reticulum membrane | Catharanthus roseus |