Literature summary for 1.14.19.58 extracted from

van Pee, K.H.; Patallo, E.P.
Flavin-dependent halogenases involved in secondary metabolism in bacteria (2006), Appl. Microbiol. Biotechnol., 70, 631-641.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-tryptophan + FADH2 + Cl- + O2 + H+	Streptomyces rugosporus	pyrroindomycin biosynthesis	5-chloro-L-tryptophan + FAD + 2 H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Streptomyces rugosporus	A4D0H5	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-tryptophan + FADH2 + Cl- + O2 + H+	-	Streptomyces rugosporus	5-chloro-L-tryptophan + FAD + 2 H2O	-	?
L-tryptophan + FADH2 + Cl- + O2 + H+	pyrroindomycin biosynthesis	Streptomyces rugosporus	5-chloro-L-tryptophan + FAD + 2 H2O	-	?

Synonyms

Synonyms	Comment	Organism
pyrH	-	Streptomyces rugosporus

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Release 2023.1 (January 2023)