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Literature summary for 1.14.19.54 extracted from

  • Winzer, T.; Kern, M.; King, A.J.; Larson, T.R.; Teodor, R.I.; Donninger, S.L.; Li, Y.; Dowle, A.A.; Cartwright, J.; Bates, R.; Ashford, D.; Thomas, J.; Walker, C.; Bowser, T.A.; Graham, I.A.
    Plant science. Morphinan biosynthesis in opium poppy requires a P450-oxidoreductase fusion protein (2015), Science, 349, 309-312 .
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.013
-
(S)-reticuline Cyp82Y2 module, pH not specified in the publication, temperature not specified in the publication Papaver somniferum

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Papaver somniferum
-
-

Organism

Organism UniProt Comment Textmining
Papaver somniferum P0DKI7 bifunctional protein, the P450 module is responsible for the conversion of (S)-reticuline to 1,2-dehydroreticuline, whereas the oxidoreductase module converts 1,2-dehydroreticuline to (R)-reticuline rather than functioning as a P450 redox partner
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-reticuline + [reduced NADPH-hemoprotein reductase] + O2
-
Papaver somniferum 1,2-dehydroreticuline + [oxidized NADPH-hemoprotein reductase] + 2 H2O
-
?

Synonyms

Synonyms Comment Organism
STORR
-
Papaver somniferum

Cofactor

Cofactor Comment Organism Structure
cytochrome P450
-
Papaver somniferum