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Literature summary for 1.14.19.5 extracted from

  • Lienard, M.A.; Lassance, J.M.; Wang, H.L.; Zhao, C.H.; Piskur, J.; Johansson, T.; Loefstedt, C.
    Elucidation of the sex-pheromone biosynthesis producing 5,7-dodecadienes in Dendrolimus punctatus (Lepidoptera: Lasiocampidae) reveals DELTA 11- and DELTA 9-desaturases with unusual catalytic properties (2010), Insect Biochem. Mol. Biol., 40, 440-452.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
heterologously expressed in Saccharomyces cerevisiae Dendrolimus punctatus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Dendrolimus punctatus heterologous expression in yeast shows that Dpu-D11-LPAE produces large amounts of DELTA11-monoenoic acids, in particular the Z11-16:Me and Z11-18:Me in a 1.5:1 ratio. When supplemented with the Z9-16:Me, yeast extracts of Dpu-D112-LPAE contained no 9,11-16:Me, but contain small amounts of E9,Z11-and E9,E11-16:Me when supplemented with E9-16:Me ?
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?
additional information Dendrolimus punctatus heterologous expression in yeast shows that Dpu-DELTA11-APSQ produces a series of mono-unsaturated products. These monoenes are identified as DELTA8-12:Me, DELTA 8-14:Me and DELTA 8-16:Me. When supplemented with the Z9-16:acid, yeast cells transformed with Dpu-DELTA11-APSQ do not produce the DELTA8-unsaturated fatty acid methyl esters, but produce significant amount of di-unsaturated 9,11-C16 methylesters ?
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?

Organism

Organism UniProt Comment Textmining
Dendrolimus punctatus
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Source Tissue

Source Tissue Comment Organism Textmining
fat body
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Dendrolimus punctatus
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pheromone gland
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Dendrolimus punctatus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information heterologous expression in yeast shows that Dpu-D11-LPAE produces large amounts of DELTA11-monoenoic acids, in particular the Z11-16:Me and Z11-18:Me in a 1.5:1 ratio. When supplemented with the Z9-16:Me, yeast extracts of Dpu-D112-LPAE contained no 9,11-16:Me, but contain small amounts of E9,Z11-and E9,E11-16:Me when supplemented with E9-16:Me Dendrolimus punctatus ?
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?
additional information heterologous expression in yeast shows that Dpu-DELTA11-APSQ produces a series of mono-unsaturated products. These monoenes are identified as DELTA8-12:Me, DELTA 8-14:Me and DELTA 8-16:Me. When supplemented with the Z9-16:acid, yeast cells transformed with Dpu-DELTA11-APSQ do not produce the DELTA8-unsaturated fatty acid methyl esters, but produce significant amount of di-unsaturated 9,11-C16 methylesters Dendrolimus punctatus ?
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?

Synonyms

Synonyms Comment Organism
DELTA11-fatty-acid desaturase
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Dendrolimus punctatus
Dpu-DELTA11-APSQ
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Dendrolimus punctatus
Dpu-DELTA11-LPAE
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Dendrolimus punctatus

General Information

General Information Comment Organism
metabolism functional expression of Dpu-DELTA11-APSQ cDNA belonging to the D11-subfamily, shows that is catalyses the formation of unsaturated fatty acyls that can be chain-shortened by beta-oxidation and subsequently reduced to the alcohol components Dendrolimus punctatus
metabolism functional expression of Dpu-DELTA11-LPAE cDNA belonging to the D11-subfamily, shows that is catalyses the formation of unsaturated fatty acyls that can be chain-shortened by beta-oxidation and subsequently reduced to the alcohol components Dendrolimus punctatus