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Literature summary for 1.14.19.47 extracted from

  • Xie, D.; Chen, F.; Lin, S.; Wang, S.; You, C.; Monroig, O.; Tocher, D.R.; Li, Y.
    Cloning, functional characterization and nutritional regulation of DELTA6 fatty acyl desaturase in the herbivorous euryhaline teleost Scatophagus argus (2014), PLoS ONE, 9, e90200 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
heterologous expression in yeast Scatophagus argus

Organism

Organism UniProt Comment Textmining
Scatophagus argus V9PQI1
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Source Tissue

Source Tissue Comment Organism Textmining
adipose tissue highest DELTA6fad mRNA expression is detected in liver followed by brain, with lower expression in other tissues including intestine, eye, muscle, adipose, heart kidney and gill, and lowest expression in stomach and spleen Scatophagus argus
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brain highest DELTA6fad mRNA expression is detected in liver followed by brain, with lower expression in other tissues including intestine, eye, muscle, adipose, heart kidney and gill, and lowest expression in stomach and spleen Scatophagus argus
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eye highest DELTA6fad mRNA expression is detected in liver followed by brain, with lower expression in other tissues including intestine, eye, muscle, adipose, heart kidney and gill, and lowest expression in stomach and spleen Scatophagus argus
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gill highest DELTA6fad mRNA expression is detected in liver followed by brain, with lower expression in other tissues including intestine, eye, muscle, adipose, heart kidney and gill, and lowest expression in stomach and spleen Scatophagus argus
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heart highest DELTA6fad mRNA expression is detected in liver followed by brain, with lower expression in other tissues including intestine, eye, muscle, adipose, heart kidney and gill, and lowest expression in stomach and spleen Scatophagus argus
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intestine highest DELTA6fad mRNA expression is detected in liver followed by brain, with lower expression in other tissues including intestine, eye, muscle, adipose, heart kidney and gill, and lowest expression in stomach and spleen Scatophagus argus
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kidney highest DELTA6fad mRNA expression is detected in liver followed by brain, with lower expression in other tissues including intestine, eye, muscle, adipose, heart kidney and gill, and lowest expression in stomach and spleen Scatophagus argus
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liver highest DELTA6fad mRNA expression is detected in liver followed by brain, with lower expression in other tissues including intestine, eye, muscle, adipose, heart kidney and gill, and lowest expression in stomach and spleen Scatophagus argus
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muscle highest DELTA6fad mRNA expression is detected in liver followed by brain, with lower expression in other tissues including intestine, eye, muscle, adipose, heart kidney and gill, and lowest expression in stomach and spleen Scatophagus argus
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spleen highest DELTA6fad mRNA expression is detected in liver followed by brain, with lower expression in other tissues including intestine, eye, muscle, adipose, heart kidney and gill, and lowest expression in stomach and spleen Scatophagus argus
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stomach highest DELTA6fad mRNA expression is detected in liver followed by brain, with lower expression in other tissues including intestine, eye, muscle, adipose, heart kidney and gill, and lowest expression in stomach and spleen Scatophagus argus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the protein product of the cDNA efficiently converts fatty acids 18:3n-3 and 18:2n-6 to 18:4n-3 and 18:3n-6, respectively, indicating DELTA6 desaturation activity Scatophagus argus ?
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Expression

Organism Comment Expression
Scatophagus argus expression of DELTA6fad is significantly affected by dietary lipid and, especially, fatty acid composition, with highest expression of mRNA in liver of fish fed a diet with a ratio of 18:3n-3/18:2n-6 of 1.72:1 up