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Literature summary for 1.14.19.3 extracted from

  • Vaittinen, M.; Walle, P.; Kuosmanen, E.; Maennistoe, V.; Kaekelae, P.; Agren, J.; Schwab, U.; Pihlajamaeki, J.
    FADS2 genotype regulates delta-6 desaturase activity and inflammation in human adipose tissue (2016), J. Lipid Res., 57, 56-65 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene FADS2, rs174616 genotype, genotyping Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O95864
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adipose tissue subcutaneous adipose tissue and visceral adipose tissue Homo sapiens
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Synonyms

Synonyms Comment Organism
D6D
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Homo sapiens
FA desaturase 2
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Homo sapiens
FADS2
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Homo sapiens

General Information

General Information Comment Organism
physiological function the FADS2 genotype regulates delta-6 desaturase activity and inflammation in human adipose tissue, association between fatty acid metabolism and adipose tissue inflammation in the Kuopio obesity surgery study, altered interleukin-1beta and NF-kappaB pathway gene expressio, overview. D6D enzyme activity in serum triglyceride fraction correlates with interleukin-1beta expression in subcutaneous adipose tissue. Surgery-induced weight loss is correlated with genotype FADS2 Homo sapiens