Cloned (Comment) | Organism |
---|---|
gene d6-des, DNA and amino acid sequence determination and analysis, sequence comparisons | Echium amoenum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha-linolenoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ | Echium amoenum | - |
stearidonoyl-CoA + 2 ferricytochrome b5 + 2 H2O | - |
? | |
linoleoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ | Echium amoenum | - |
gamma-linolenoyl-CoA + 2 ferricytochrome b5 + 2 H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Echium amoenum | D2KP14 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
seed | - |
Echium amoenum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha-linolenoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ | - |
Echium amoenum | stearidonoyl-CoA + 2 ferricytochrome b5 + 2 H2O | - |
? | |
linoleoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ | - |
Echium amoenum | gamma-linolenoyl-CoA + 2 ferricytochrome b5 + 2 H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | secondary structure of the enzyme deduced from its primary structure using computational simulation | Echium amoenum |
Synonyms | Comment | Organism |
---|---|---|
d6-des | - |
Echium amoenum |
D6Des | - |
Echium amoenum |
DELTA-6 desaturase | - |
Echium amoenum |
EaD6DES | - |
Echium amoenum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome b5 | the enzyme contains a cytochrome b5 domain and three conserved histidine-rich motifs | Echium amoenum |
General Information | Comment | Organism |
---|---|---|
evolution | weak activity and different secondary structure of delta-6 desaturase (D6DES) in Echium amoenum compared with D6DESs of other species | Echium amoenum |
additional information | analysis of functional sites and substrate binding motifs of D6DES enzyme, overview | Echium amoenum |
physiological function | D6DES enzyme is responsible for converting linoleic acid and alpha-linolenic acid to gamma-linolenoic acid and stearidonic acid | Echium amoenum |