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Literature summary for 1.14.19.3 extracted from

  • Ge, L.; Gordon, J.S.; Hsuan, C.; Stenn, K.; Prouty, S.M.
    Identification of the DELTA-6 desaturase of human sebaceous glands: expression and enzyme activity (2003), J. Invest. Dermatol., 120, 707-714.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
palmitate + AH2 + O2 Homo sapiens the enzyme is a component of the lipid metabolic pathway that converts the essential fatty acids linoleate and alpha-linolenate into long-chain polyunsaturated fatty acids. The DELTA-6 desaturase/FADS2 expressed in human sebocytes catalyzes the conversion of palmitate into sapienate sapienate + A + H2O
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens O95864
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-

Source Tissue

Source Tissue Comment Organism Textmining
sebaceous gland
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Homo sapiens
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skin
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Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
palmitate + AH2 + O2
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Homo sapiens sapienate + A + H2O
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?
palmitate + AH2 + O2 the enzyme is a component of the lipid metabolic pathway that converts the essential fatty acids linoleate and alpha-linolenate into long-chain polyunsaturated fatty acids. The DELTA-6 desaturase/FADS2 expressed in human sebocytes catalyzes the conversion of palmitate into sapienate Homo sapiens sapienate + A + H2O
-
?

Synonyms

Synonyms Comment Organism
DELTA-6 desaturase
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Homo sapiens
FADS2
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Homo sapiens
fatty acid desaturase-2
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Homo sapiens