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Literature summary for 1.14.19.22 extracted from

  • Kearns, E.V.; Hugly, S.; Somerville, C.R.
    The role of cytochrome b5 in DELTA12 desaturation of oleic acid by microsomes of safflower (Carthamus tinctorius L.) (1991), Arch. Biochem. Biophys., 284, 431-436.
    View publication on PubMed
Search for more literature for 1.14.19.22

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Carthamus tinctorius
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
oleoyl-[CoA] + ferrocytochrome b5 + O2 + H+ Carthamus tinctorius
-
 linoleoyl-[CoA] + ferricytochrome b5 + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Carthamus tinctorius
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
floret
-
 Carthamus tinctorius
-
flower
-
 Carthamus tinctorius
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
oleoyl-[CoA] + ferrocytochrome b5 + O2 + H+
-
 Carthamus tinctorius linoleoyl-[CoA] + ferricytochrome b5 + H2O
-
 ?
oleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ the IgG fraction from ascites fluid inhibits 62% of NADH-dependent cytochrome c reduction in safflower (Carthamus tinctorius L.) microsomes. These antibodies also block desaturation of oleic acid to linoleic acid in lipids of Carthamus tinctorius microsomes by 93%, suggesting that cytochrome b5 is the electron donor for the DELTA12 desaturase Carthamus tinctorius linoleoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O
-
 ?

Synonyms

Synonyms Comment Organism
DELTA12 desaturase
-
 Carthamus tinctorius

Cofactor

Cofactor Comment Organism Structure
cytochrome b5
-
 Carthamus tinctorius
NAD(P)H
-
 Carthamus tinctorius