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Literature summary for 1.14.19.20 extracted from

  • Nusblat, A.D.; Najle, S.R.; Tomazic, M.L.; Uttaro, A.D.; Nudel, C.B.
    C-5(6) sterol desaturase from Tetrahymena thermophila: Gene identification and knockout, sequence analysis, and comparison to other C-5(6) sterol desaturases (2009), Eukaryot. Cell, 8, 1287-1297.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.19.20

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Tetrahymena thermophila
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5alpha-cholest-22-en-3beta-ol + ferrocytochrmoe b5 + H+ + O2 Tetrahymena thermophila
-
 cholesta-5,22-dien-3beta-ol + ferricytochrome b5 + 2 H2O
-
 ?
5alpha-cholest-22-en-3beta-ol + ferrocytochrmoe b5 + H+ + O2 Tetrahymena thermophila CU428
-
 cholesta-5,22-dien-3beta-ol + ferricytochrome b5 + 2 H2O
-
 ?
5alpha-cholest-7-en-3beta-ol + ferrocytochrome b5 + H+ + O2 Tetrahymena thermophila
-
 cholesta-5,7-dien-3beta-ol + ferricytochrome b5 + 2 H2O
-
 ?
5alpha-cholest-7-en-3beta-ol + ferrocytochrome b5 + H+ + O2 Tetrahymena thermophila CU428
-
 cholesta-5,7-dien-3beta-ol + ferricytochrome b5 + 2 H2O
-
 ?
5alpha-cholesta-7,22-dien-3beta-ol + ferrocytochrome b5 + H+ + O2 Tetrahymena thermophila
-
 cholesta-5,7,22-trien-3beta-ol + ferricytochrome b5 + 2 H2O
-
 ?
5alpha-cholesta-7,22-dien-3beta-ol + ferrocytochrome b5 + H+ + O2 Tetrahymena thermophila CU428
-
 cholesta-5,7,22-trien-3beta-ol + ferricytochrome b5 + 2 H2O
-
 ?
5alpha-cholestan-3beta-ol + ferrocytochrome b5 + H+ + O2 Tetrahymena thermophila
-
 cholest-5-en-3beta-ol + ferricytochrome b5 + 2 H2O
-
 ?
5alpha-cholestan-3beta-ol + ferrocytochrome b5 + H+ + O2 Tetrahymena thermophila CU428
-
 cholest-5-en-3beta-ol + ferricytochrome b5 + 2 H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Tetrahymena thermophila C4PFX1
-
-
Tetrahymena thermophila CU428 C4PFX1
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5alpha-cholest-22-en-3beta-ol + ferrocytochrmoe b5 + H+ + O2
-
 Tetrahymena thermophila cholesta-5,22-dien-3beta-ol + ferricytochrome b5 + 2 H2O
-
 ?
5alpha-cholest-22-en-3beta-ol + ferrocytochrmoe b5 + H+ + O2
-
 Tetrahymena thermophila CU428 cholesta-5,22-dien-3beta-ol + ferricytochrome b5 + 2 H2O
-
 ?
5alpha-cholest-7-en-3beta-ol + ferrocytochrome b5 + H+ + O2
-
 Tetrahymena thermophila cholesta-5,7-dien-3beta-ol + ferricytochrome b5 + 2 H2O
-
 ?
5alpha-cholest-7-en-3beta-ol + ferrocytochrome b5 + H+ + O2
-
 Tetrahymena thermophila CU428 cholesta-5,7-dien-3beta-ol + ferricytochrome b5 + 2 H2O
-
 ?
5alpha-cholesta-7,22-dien-3beta-ol + ferrocytochrome b5 + H+ + O2
-
 Tetrahymena thermophila cholesta-5,7,22-trien-3beta-ol + ferricytochrome b5 + 2 H2O
-
 ?
5alpha-cholesta-7,22-dien-3beta-ol + ferrocytochrome b5 + H+ + O2
-
 Tetrahymena thermophila CU428 cholesta-5,7,22-trien-3beta-ol + ferricytochrome b5 + 2 H2O
-
 ?
5alpha-cholestan-3beta-ol + ferrocytochrome b5 + H+ + O2
-
 Tetrahymena thermophila cholest-5-en-3beta-ol + ferricytochrome b5 + 2 H2O
-
 ?
5alpha-cholestan-3beta-ol + ferrocytochrome b5 + H+ + O2
-
 Tetrahymena thermophila CU428 cholest-5-en-3beta-ol + ferricytochrome b5 + 2 H2O
-
 ?

Synonyms

Synonyms Comment Organism
C-5(6) sterol desaturase
-
 Tetrahymena thermophila
Des5Ap
-
 Tetrahymena thermophila

Cofactor

Cofactor Comment Organism Structure
NADH
-
 Tetrahymena thermophila