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Literature summary for 1.14.19.10 extracted from

  • Slabaugh, M.; Cooper, L.; Kishore, V.; Knapp, S.; Kling, J.
    Genes affecting novel seed constituents in Limnanthes alba Benth transcriptome analysis of developing embryos and a new genetic map of meadowfoam (2015), PeerJ, 2015, e915 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene DELTA5DS, gene mapping and genotyping, Construction and annotation of a developing embryo cDNA library, gene DELTA5DS DNA and amino acid sequence determination and analysis, sequence comparisons, RT-PCR enzyme expression analysis Limnanthes alba subsp. alba

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information the enzyme lacks a chloroplastic transit peptide Limnanthes alba subsp. alba
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-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
icosanoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ Limnanthes alba subsp. alba
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(Z)-icos-5-enoyl-CoA + 2 ferricytochrome b5 + 2 H2O
-
?
additional information Limnanthes alba subsp. alba very long chain fatty acids are desaturated at the DELTA5 position ?
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?

Organism

Organism UniProt Comment Textmining
Limnanthes alba subsp. alba
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cv. MF164, var. Ross
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Source Tissue

Source Tissue Comment Organism Textmining
embryo the enzyme is highly expressed in mid-development embryos Limnanthes alba subsp. alba
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seed
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Limnanthes alba subsp. alba
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
icosanoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+
-
Limnanthes alba subsp. alba (Z)-icos-5-enoyl-CoA + 2 ferricytochrome b5 + 2 H2O
-
?
additional information very long chain fatty acids are desaturated at the DELTA5 position Limnanthes alba subsp. alba ?
-
?

Synonyms

Synonyms Comment Organism
acyl-CoA DELTA5 desaturase
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Limnanthes alba subsp. alba
Delta-5 acyl-CoA desaturase
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Limnanthes alba subsp. alba
DELTA5 desaturase
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Limnanthes alba subsp. alba
DELTA5DS
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Limnanthes alba subsp. alba

Cofactor

Cofactor Comment Organism Structure
cytochrome b5
-
Limnanthes alba subsp. alba

General Information

General Information Comment Organism
evolution the enzyme is a member of the large DELTAa9-FADS-like or ADS subfamily found in eukaryotes including vertebrates, insects, higher plants and fungi, as well as a wide range of bacteria. These non-heme, iron-containing, endoplasmic reticulum membrane-bound enzymes exhibit a diversity of subcellular localization, lipid substrate utilization, regiospecificity, and biological function Limnanthes alba subsp. alba
metabolism mapping genes in meadowfoam glucosinolate metabolism, overview Limnanthes alba subsp. alba
additional information meadowfoam seed oil is the richest known source of DELTA5 monounsaturated fatty acids and presently the sole commercial source of DELTA5-unsaturated very long chain fatty acids, a high 20:1DELTA5 phenotype of meadowfoam oil Limnanthes alba subsp. alba