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Literature summary for 1.14.19.1 extracted from

  • Dobrzyn, A.; Ntambi, J.M.
    Stearoyl-CoA desaturase as a new drug target for obesity treatment (2005), Obes. Rev., 6, 169-174.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
four stearoyl-CoA desaturase genes Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
liver on a high-fat diet the livers of wild-type mice become steatotic, stearoyl-CoA desaturase deficiency protects against liver steatosis, on a chow diet the livers of wild-type and SCD1-/- mice are normal and of similar mass Mus musculus
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additional information stearoyl-CoA desaturase deficient mice have very low levels of triglycerides in the VLDL and LDL fractions relative to the wild-type Mus musculus
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Synonyms

Synonyms Comment Organism
SCD1
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Mus musculus