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Literature summary for 1.14.19.1 extracted from

  • Biddinger, S.B.; Almind, K.; Miyazaki, M.; Kokkotou, E.; Ntambi, J.M.; Kahn, C.R.
    Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome (2005), Diabetes, 54, 1314-1323.
    View publication on PubMed
Search for more literature for 1.14.19.1

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome from liver Mus musculus
-
-

Organism

Organism UniProt Comment Textmining
Mus musculus
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 C57Bl/B6 and 129S6/SvEvTac mice
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Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Mus musculus
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skeletal muscle C57Bl/B6 mice under low-fat diet have 3 to 4 times more SCD1 transcript than 129S6/SvEvTac mice under low-fat diet, mRNA increased 3fold by high-fat feeding of 129S6/SvEvTac mice and 1.5fold by high-fat feeding of C57Bl/B6 mice Mus musculus
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0002
-
 129S6/SvEvTac mice under low-fat diet, liver microsomes, stearoyl-CoA as substrate Mus musculus
0.0004
-
 129S6/SvEvTac mice under high-fat diet, liver microsomes, stearoyl-CoA as substrate Mus musculus
0.0011
-
 C57Bl/B6 mice under low-fat diet, liver microsomes, stearoyl-CoA as substrate Mus musculus
0.0016
-
 C57Bl/B6 mice under high-fat diet, liver microsomes, stearoyl-CoA as substrate Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
stearoyl-CoA + NADH + O2
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 Mus musculus oleoyl-CoA + NAD+ + H2O
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 ?

Synonyms

Synonyms Comment Organism
SCD1
-
 Mus musculus