Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.19.1 extracted from

  • MacKenzie, D.A.; Carter, A.T.; Wongwathanarat, P.; Eagles, J.; Salt, J.; Archer, D.B.
    A third fatty acid DELTA9-desaturase from Mortierella alpina with a different substrate specificity to ole1p and ole2p (2002), Microbiology, 148, 1725-1735.
    View publication on PubMed
Search for more literature for 1.14.19.1

Cloned(Commentary)

Cloned (Comment) Organism
expression of DELTA9-3 gene in Saccharomyces cerevisiae Mortierella alpina

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Mortierella alpina 5783
-
membrane bound Mortierella alpina 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mortierella alpina long-chain polyunsaturated fatty acid biosynthetic pathway ?
-
 ?
additional information Mortierella alpina CBS 528.72 / ATCC 32222 long-chain polyunsaturated fatty acid biosynthetic pathway ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mortierella alpina
-
-
-
Mortierella alpina CBS 528.72 / ATCC 32222
-
-
-

Reaction

Reaction Comment Organism Reaction ID
stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = oleoyl-CoA + 2 ferricytochrome b5 + 2 H2O isolation of a third fatty acid DELTA9-desaturase. Higher activity with longer chain fatty acid substrates. Desaturase expression is induced significantly by increasing the ratio of carbon to nitrogen Mortierella alpina
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information long-chain polyunsaturated fatty acid biosynthetic pathway Mortierella alpina ?
-
 ?
additional information long-chain polyunsaturated fatty acid biosynthetic pathway Mortierella alpina CBS 528.72 / ATCC 32222 ?
-
 ?
palmitic acid + AH2 + O2
-
 Mortierella alpina palmitoleic acid + A + H2O
-
 ?
palmitic acid + AH2 + O2
-
 Mortierella alpina CBS 528.72 / ATCC 32222 palmitoleic acid + A + H2O
-
 ?
stearate + AH2 + O2
-
 Mortierella alpina oleate + A + 2 H2O
-
 ?
stearate + AH2 + O2
-
 Mortierella alpina CBS 528.72 / ATCC 32222 oleate + A + 2 H2O
-
 ?

Cofactor

Cofactor Comment Organism Structure
cytochrome b5 fusion, C-terminal Mortierella alpina