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Literature summary for 1.14.18.2 extracted from

  • Malykh, Y.N.; Shaw, L.; Schauer, R.
    The role of CMP-N-acetylneuraminic acid hydroxylase in determining the level of N-glycolylneuraminic acid in porcine tissues (1998), Glycoconjugate J., 15, 885-893.
    View publication on PubMed
Search for more literature for 1.14.18.2

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CMP-N-acetylneuraminate + NADH + O2 Sus scrofa the biosynthesis of the sialic acid N-glycolylneuraminic acid occurs by the action of cytidine monophosphate-N-acetylneuraminate hydroxylase. Incorporation of N-glycoloylneuraminic acid into glycoconjugates is generally controlled by the amount of hydroxylase protein expressed in a tissue CMP-N-glycoloylneuraminate + NAD+ + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart weak activity Sus scrofa
-
kidney weak activity Sus scrofa
-
liver weak activity Sus scrofa
-
lung
-
 Sus scrofa
-
lymph node
-
 Sus scrofa
-
small intestine
-
 Sus scrofa
-
spleen
-
 Sus scrofa
-
submandibular gland
-
 Sus scrofa
-
thymus
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-N-acetylneuraminate + NADH + O2
-
 Sus scrofa CMP-N-glycoloylneuraminate + NAD+ + H2O
-
 ?
CMP-N-acetylneuraminate + NADH + O2 the biosynthesis of the sialic acid N-glycolylneuraminic acid occurs by the action of cytidine monophosphate-N-acetylneuraminate hydroxylase. Incorporation of N-glycoloylneuraminic acid into glycoconjugates is generally controlled by the amount of hydroxylase protein expressed in a tissue Sus scrofa CMP-N-glycoloylneuraminate + NAD+ + H2O
-
 ?

Cofactor

Cofactor Comment Organism Structure
NADH
-
 Sus scrofa