Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.18.10 extracted from

  • Pascal, S.; Taton, M.; Rahier, A.
    Oxidative C4-demethylation of 24-methylene cycloartanol by a cyanide-sensitive enzymatic system from higher plant microsomes (1990), Biochem. Biophys. Res. Commun., 172, 98-106 .
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
cyanide 5% residual activity at 0.05 mM Zea mays
menadione 39% residual activity at 0.05 mM Zea mays
additional information not inhibited by CO (saturated), LAB 170250F, and tetcyclacis Zea mays

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Zea mays
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
24-methylidenecycloartanol + NADPH + O2 + H+ Zea mays overall reaction cycloeucalenol + NADP+ + H2O
-
?

Organism

Organism UniProt Comment Textmining
Zea mays
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
24-methylidenecycloartanol + 2 ferrocytochrome b5 + O2 + 2 H+
-
Zea mays 4alpha-(hydroxymethyl)-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + 2 ferricytochrome B5 + H2O
-
?
24-methylidenecycloartanol + NADPH + O2 + H+ overall reaction Zea mays cycloeucalenol + NADP+ + H2O
-
?
4alpha-(hydroxymethyl)-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + 2 ferrocytochrome b5 + O2 + 2 H+
-
Zea mays 4alpha-formyl-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + 2 ferricytochrome b5 + H2O
-
?
cycloeucalenone + NADPH + O2 + H+
-
Zea mays cycloeucalenol + NADP+ + H2O
-
?

Synonyms

Synonyms Comment Organism
4,4-dimethyl 4-demethylase
-
Zea mays

Cofactor

Cofactor Comment Organism Structure
NADPH required Zea mays

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.008
-
at pH 7.6 and 30°C Zea mays cyanide