Inhibitors | Comment | Organism | Structure |
---|---|---|---|
hydroquinone | - |
Agaricus bisporus | |
hydroquinone | - |
Homo sapiens | |
KFEKKFEK | - |
Agaricus bisporus | |
L-Pro-L-Leu-Gly | - |
Agaricus bisporus | |
additional information | not inhibited by VLLK and KFEFKFEF | Agaricus bisporus | |
RADSRADC | - |
Agaricus bisporus | |
RADSRADC | 25% inhibition at 0.1 mM | Homo sapiens | |
SFLLRN | - |
Agaricus bisporus | |
YRSRKYSSWY | - |
Agaricus bisporus | |
YRSRKYSSWY | 35% inhibition at 0.1 mM | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agaricus bisporus | - |
- |
- |
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
melanocyte | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-DOPA + O2 | - |
Homo sapiens | dopaquinone + H2O | - |
? | |
L-DOPA + O2 | - |
Agaricus bisporus | dopaquinone + H2O | - |
? | |
L-tyrosine + O2 | - |
Homo sapiens | L-DOPA + H2O | - |
? | |
L-tyrosine + O2 | - |
Agaricus bisporus | L-DOPA + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
tyrosinase | - |
Homo sapiens |
tyrosinase | - |
Agaricus bisporus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.04 | - |
in 0.67 mM potassium phosphate buffer (pH 6.8), at 37°C | Agaricus bisporus | YRSRKYSSWY | |
0.123 | - |
in 0.67 mM potassium phosphate buffer (pH 6.8), at 37°C | Agaricus bisporus | RADSRADC | |
2.73 | - |
in 0.67 mM potassium phosphate buffer (pH 6.8), at 37°C | Agaricus bisporus | L-Pro-L-Leu-Gly | |
3.6 | - |
in 0.67 mM potassium phosphate buffer (pH 6.8), at 37°C | Agaricus bisporus | KFEKKFEK | |
8 | - |
in 0.67 mM potassium phosphate buffer (pH 6.8), at 37°C | Agaricus bisporus | SFLLRN |