Literature summary for 1.14.17.4 extracted from

Kosugi, Y.; Matsuoka, A.; Higashi, A.; Toyohara, N.; Satoh, S.
2-Aminooxyisobutyric acid inhibits the in vitro activities of both 1-aminocyclopropane-1-carboxylate (ACC) synthase and ACC oxidase in ethylene biosynthetic pathway and prolongs vase life of cut carnation flowers (2014), J. Plant Biol., 57, 218-224 .

No PubMed abstract available

Search for more literature for 1.14.17.4

Application

Application	Comment	Organism
additional information	potential of 2-aminooxyisobutyric acid as a preservative for carnations and other ornamentals, in which ethylene plays a key role in the induction of senescence, by inhibition of 1-aminocyclopropane-1-carboxylate oxidase. 2-aminooxyisobutyric acid at 1 mM causes 91.5% reduction of maximum ethylene production rate as compared to the control in cut Excerea carnation flowers undergoing senescence, thereby lengthening their vase life to 7 d from 3 d of the control flowers. The compound also extends significantly the vase life of cut flowers of Pax carnation, and tends to do so in Primero Mango carnation. Suppression of flower senescence, overview	Dianthus caryophyllus

Cloned(Commentary)

Cloned (Comment)	Organism
recombinant expression in Escherichia coli	Dianthus caryophyllus

Inhibitors

Inhibitors	Comment	Organism	Structure
2-aminoisobutyric acid	22.5% inhibition at 10 mM	Dianthus caryophyllus
2-aminooxyisobutyric acid	inhibits the in vitro activities of both 1-aminocyclopropane-1-carboxylate (ACC) synthase and ACC oxidase in ethylene biosynthetic pathway, 16.3% inhibition of recombinnat enzyme at 10 mM	Dianthus caryophyllus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1-aminocyclopropane-1-carboxylate + ascorbate + O2	Dianthus caryophyllus	-	ethylene + cyanide + dehydroascorbate + CO2 + 2 H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Dianthus caryophyllus	P31528	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
flower	-	Dianthus caryophyllus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1-aminocyclopropane-1-carboxylate + ascorbate + O2	-	Dianthus caryophyllus	ethylene + cyanide + dehydroascorbate + CO2 + 2 H2O	-	?

Synonyms

Synonyms	Comment	Organism
ACC oxidase	-	Dianthus caryophyllus

Cofactor

Cofactor	Comment	Organism	Structure
ascorbate	-	Dianthus caryophyllus

General Information

General Information	Comment	Organism
metabolism	the enzyme catalyzes the terminal step in ethylene biosynthesis	Dianthus caryophyllus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)