Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
copper | - |
Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
87000 | - |
determined by SDS-PAGE and Western Blot analysis | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | PAM is the only enzyme capable of amidating peptides, amidated peptides are numerous | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hypothalamus | - |
Mus musculus | - |
pituitary gland | - |
Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.000012 | - |
PAM+/- mouse, POA, hypothalamus | Mus musculus |
0.000015 | - |
PAM+/- mouse, PVN, hypothalamus | Mus musculus |
0.000037 | - |
wild-type mouse, POA, hypothalamus | Mus musculus |
0.00004 | - |
wild-type mouse, PVN, hypothalamus | Mus musculus |
0.000043 | - |
PAM+/- mouse, pituitary | Mus musculus |
0.00008 | - |
wild-type mouse, pituitary | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | PAM is the only enzyme capable of amidating peptides, amidated peptides are numerous | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PAM | - |
Mus musculus |
peptidylglycine alpha-amidating monooxygenase | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | regulation of the hypothalamic-pituitary-thyroid axis and body temperature are selected for evaluation | Mus musculus |