Protein Variants | Comment | Organism |
---|---|---|
A318S | the mutation does not influence enzyme activity | Homo sapiens |
G482R | the mutation has subsequent effect on the activity of the enzyme as it is present close to the active site | Homo sapiens |
L317P | the mutation does not influence enzyme activity | Homo sapiens |
R549C | the mutation causes abnormal oligomerization through non-native disulfide bond formation | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
nepicastat | - |
Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
copper | contains copper | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dopamine + ascorbate + O2 | Homo sapiens | - |
noradrenaline + dehydroascorbate + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P09172 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dopamine + ascorbate + O2 | - |
Homo sapiens | noradrenaline + dehydroascorbate + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DBH | - |
Homo sapiens |
dopamine beta-hydroxylase | - |
Homo sapiens |