Cloned (Comment) | Organism |
---|---|
expressed in Chinese hamster ovary cells | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Iron | the enzyme uses a di-iron centre for catalysis | Rattus norvegicus | |
Iron | the enzyme uses a di-iron centre for catalysis | Caenorhabditis elegans | |
Iron | the enzyme uses a di-iron centre for catalysis | Danio rerio |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
40500 | - |
x * 40500, SDS-PAGE | Rattus norvegicus |
40500 | - |
x * 40500, SDS-PAGE | Caenorhabditis elegans |
40500 | - |
x * 40500, SDS-PAGE | Danio rerio |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-O-alkyl-sn-glycerol 3-phosphate + tetrahydrobiopterin + O2 | Caenorhabditis elegans | - |
1-O-(1-hydroxyalkyl)-sn-glycerol 3-phosphate + 6,7-[8]-dihydrobiopterin + H2O | - |
? | |
1-O-alkyl-sn-glycerol 3-phosphate + tetrahydrobiopterin + O2 | Danio rerio | - |
1-O-(1-hydroxyalkyl)-sn-glycerol 3-phosphate + 6,7-[8]-dihydrobiopterin + H2O | - |
? | |
lyso-alkyl-glycerol phospholipid + tetrahydrobiopterin + O2 | Rattus norvegicus | - |
1-O-(1-hydroxyalkyl)-sn-glycerol + 6,7-[8]-dihydrobiopterin + H2O | - |
? | |
lyso-platelet activating factor + tetrahydrobiopterin + O2 | Rattus norvegicus | good substrate | ? | - |
? | |
lyso-platelet activating factor + tetrahydrobiopterin + O2 | Caenorhabditis elegans | good substrate | ? | - |
? | |
lyso-platelet activating factor + tetrahydrobiopterin + O2 | Danio rerio | good substrate | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caenorhabditis elegans | - |
- |
- |
Danio rerio | - |
- |
- |
no activity in Drosophila melanogaster | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
6-aminohexyl Sepharose column chromatography, diethylaminoethyl cellulose column chromatography, sucrose density centrifugation, and hexadecylglycerol affinity chromatography | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-O-alkyl-sn-glycerol 3-phosphate + tetrahydrobiopterin + O2 | - |
Caenorhabditis elegans | 1-O-(1-hydroxyalkyl)-sn-glycerol 3-phosphate + 6,7-[8]-dihydrobiopterin + H2O | - |
? | |
1-O-alkyl-sn-glycerol 3-phosphate + tetrahydrobiopterin + O2 | - |
Danio rerio | 1-O-(1-hydroxyalkyl)-sn-glycerol 3-phosphate + 6,7-[8]-dihydrobiopterin + H2O | - |
? | |
1-O-pyrenedecyl-glycerol + tetrahydrobiopterin + O2 | - |
Rattus norvegicus | ? | - |
? | |
1-O-pyrenedecyl-glycerol + tetrahydrobiopterin + O2 | - |
Caenorhabditis elegans | ? | - |
? | |
1-O-pyrenedecyl-glycerol + tetrahydrobiopterin + O2 | - |
Danio rerio | ? | - |
? | |
hexadecylglycerol + tetrahydrobiopterin + O2 | - |
Rattus norvegicus | ? | - |
? | |
hexadecylglycerol + tetrahydrobiopterin + O2 | - |
Caenorhabditis elegans | ? | - |
? | |
hexadecylglycerol + tetrahydrobiopterin + O2 | - |
Danio rerio | ? | - |
? | |
lyso-alkyl-glycerol phospholipid + tetrahydrobiopterin + O2 | - |
Rattus norvegicus | 1-O-(1-hydroxyalkyl)-sn-glycerol + 6,7-[8]-dihydrobiopterin + H2O | - |
? | |
lyso-platelet activating factor + tetrahydrobiopterin + O2 | good substrate | Rattus norvegicus | ? | - |
? | |
lyso-platelet activating factor + tetrahydrobiopterin + O2 | good substrate | Caenorhabditis elegans | ? | - |
? | |
lyso-platelet activating factor + tetrahydrobiopterin + O2 | good substrate | Danio rerio | ? | - |
? | |
additional information | 1-O-alkyl-sn glycerol-3-phosphate is no substrate | Rattus norvegicus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 40500, SDS-PAGE | Rattus norvegicus |
? | x * 40500, SDS-PAGE | Caenorhabditis elegans |
? | x * 40500, SDS-PAGE | Danio rerio |
Synonyms | Comment | Organism |
---|---|---|
glyceryl ether monooxygenase | - |
Rattus norvegicus |
glyceryl ether monooxygenase | - |
Caenorhabditis elegans |
glyceryl ether monooxygenase | - |
Danio rerio |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
tetrahydrobiopterin | dependent on | Rattus norvegicus | |
tetrahydrobiopterin | dependent on | Caenorhabditis elegans | |
tetrahydrobiopterin | dependent on | Danio rerio |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme has an anti-inflammatory action by switching off the platelet activating factor signal by irreversible degradation of its lyso form | Rattus norvegicus |