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Literature summary for 1.14.16.4 extracted from

  • Laurent, L.; Deroy, K.; St-Pierre, J.; Cote, F.; Sanderson, J.T.; Vaillancourt, C.
    Human placenta expresses both peripheral and neuronal isoform of tryptophan hydroxylase (2017), Biochimie, 140, 159-165 .
    View publication on PubMed
Search for more literature for 1.14.16.4

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-tryptophan + tetrahydrobiopterin + O2 Mus musculus
-
 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
-
 ?
L-tryptophan + tetrahydrobiopterin + O2 Homo sapiens
-
 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
BeWo cell
-
 Homo sapiens
-
capillary of fetus Homo sapiens
-
decidual cell
-
 Homo sapiens
-
extravillous cytotrophoblast
-
 Homo sapiens
-
HIPEC-65 cell
-
 Homo sapiens
-
HTR-8 cell
-
 Homo sapiens
-
HTR8/SVneo cell
-
 Homo sapiens
-
JEG-3 cell
-
 Homo sapiens
-
PBMC cell
-
 Homo sapiens
-
placenta
-
 Mus musculus
-
placenta
-
 Homo sapiens
-
primary cell culture
-
 Homo sapiens
-
syncytiotrophoblast
-
 Homo sapiens
-
trophoblast
-
 Homo sapiens
-
villous cytotrophoblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tryptophan + tetrahydrobiopterin + O2
-
 Mus musculus 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
-
 ?
L-tryptophan + tetrahydrobiopterin + O2
-
 Homo sapiens 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
-
 ?

Synonyms

Synonyms Comment Organism
TPH1 isoform Mus musculus
TPH1 isoform Homo sapiens
TPH2 isoform Mus musculus
TPH2 isoform Homo sapiens
tryptophan hydroxylase
-
 Mus musculus
tryptophan hydroxylase
-
 Homo sapiens