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Literature summary for 1.14.16.2 extracted from

  • Qiao, L.; Du, M.; Liang, X.; Hao, Y.; He, X.; Si, F.; Mei, T.; Chen, B.
    Tyrosine Hydroxylase is crucial for maintaining pupal tanning and immunity in Anopheles sinensis (2016), Sci. Rep., 6, 29835 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
-
Anopheles sinensis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-tyrosine + tetrahydrobiopterin + O2 Anopheles sinensis
-
L-dopa + 4a-hydroxytetrahydrobiopterin + H2O
-
?

Organism

Organism UniProt Comment Textmining
Anopheles sinensis A0A084W0Q1 strain WX-LS
-

Source Tissue

Source Tissue Comment Organism Textmining
cuticle
-
Anopheles sinensis
-
pupa
-
Anopheles sinensis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tyrosine + tetrahydrobiopterin + O2
-
Anopheles sinensis L-dopa + 4a-hydroxytetrahydrobiopterin + H2O
-
?

Synonyms

Synonyms Comment Organism
tyrosine hydroxylase
-
Anopheles sinensis

Expression

Organism Comment Expression
Anopheles sinensis during pupal metamorphosis, enzyme expression is upregulated during the late stage of development up

General Information

General Information Comment Organism
malfunction suppression of enzyme expression results in cuticle tanning defects and impaired immunity with dramatically decreased survival rates and life spans of pupae Anopheles sinensis
physiological function the enzyme is crucial for maintaining pupal tanning and immunity in Anopheles sinensis Anopheles sinensis