Literature summary for 1.14.16.2 extracted from

Rosmaninho-Salgado, J.; Araujo, I.M.; Alvaro, A.R.; Mendes, A.F.; Ferreira, L.; Grouzmann, E.; Mota, A.; Duarte, E.P.; Cavadas, C.
Regulation of catecholamine release and tyrosine hydroxylase in human adrenal chromaffin cells by interleukin-1beta: role of neuropeptide Y and nitric oxide (2009), J. Neurochem., 109, 911-922.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	10 ng/ml interleukin-1beta induces the phosphorylation of tyrosine hydroxylase at Ser40 1.4fold, 0.0001 mM forskolin induces a 1.5fold increase on tyrosine hydroxylase phosphorylation	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
alpha-methyl-p-tyrosine	complete inhibition at 0.001 mM	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
adrenal gland	-	Homo sapiens	-
chromaffin cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
tyrosine hydroxylase	-	Homo sapiens

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Release 2023.1 (January 2023)