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BRENDA support

Literature summary for 1.14.16.2 extracted from

  • Nordquist, R.E.; Savignac, H.; Pauly-Evers, M.; Walker, G.; Knoflach, F.; Borroni, E.; Glaentzlin, P.; Bohrmann, B.; Messer, J.; Ozmen, L.; Albientz, A.; Spooren, W.
    Characterization of behavioral response to amphetamine, tyrosine hydroxylase levels, and dopamine receptor levels in neurokinin 3 receptor knockout mice (2008), Behav. Pharmacol., 19, 518-529.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information amphetamines upregulate the enzymein the central nervous system and the olfactory tubercle, overview Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information construction of neurokinin 3 receptor knockout mice, the mutant mice do not show altered tyrosine hydroxylase levels in the caudate putamen or nucleus accumbens, but show decreased enzyme levels in the olfactory tuberculum, phenotype, overview Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
olfactory tubercle
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Mus musculus
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