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Literature summary for 1.14.16.2 extracted from
- Inhibition of rodent brain monoamine oxidase and tyrosine hydroxylase by endogenous compounds - 1,2,3,4-tetrahydro-isoquinoline alkaloids (2005), Pol. J. Pharmacol., 56, 727-734.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,2,3,4-tetrahydropapaveroline | 50% inhibition at 7.5 microM | Rattus norvegicus |  |
| salsolinol | 50% inhibition at 35.4 microM and 4.1 microM when assayed at 6,7-dimethyl-2-amino-4-hydroxy-5,6,7,8-tetrahydopteridine concentration of 0.5 mM or 0.25 mM, respectively | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| corpus striatum | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tyrosine + 6,7-dimethyl-2-amino-4-hydroxy-5,6,7,8-tetrahydopteridine + O2 | - |
Rattus norvegicus | 3,4-dihydroxyphenylalanine + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TH | - |
Rattus norvegicus |
| tyrosine hydroxylase | - |
Rattus norvegicus |
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