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Literature summary for 1.14.16.2 extracted from
- Analytical characterization of a sensitive radioassay for tyrosine hydroxylase activity in rodent striatum (2004), Neurochem. Res., 29, 1467-1472.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| DL-6-methyl-5,6,7,8-tetrahydropterine | 3.0-4.5 mM | Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
| caudate putamen | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Tyr + DL-6-methyl-5,6,7,8-tetrahydropterin + O2 | significant activity at a concetration of DL-6-methyl-5,6,7,8-tetrahydropterine: 1.5 mM | Rattus norvegicus | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5.5 | 6 | striatal homogenate | Rattus norvegicus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5.5 | 6.8 | pH 5.0: less than 5% of maximal activity, pH 5.5-6.0: optimum, pH 6.8: about 30% of maximal activity, striatal homogenate | Rattus norvegicus |
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Release 2023.1 (January 2023)
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