Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50000 | - |
4 * 50000, SDS-PAGE | Homo sapiens |
50000 | - |
4 * 50000, SDS-PAGE | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-phenylalanine + tetrahydrobiopterin + O2 | Homo sapiens | - |
L-tyrosine + 4a-hydroxytetrahydrobiopterin | - |
? | |
L-phenylalanine + tetrahydrobiopterin + O2 | Rattus norvegicus | - |
L-tyrosine + 4a-hydroxytetrahydrobiopterin | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | P04176 | - |
- |
Purification (Comment) | Organism |
---|---|
HiTrap Q column chromatography | Homo sapiens |
phenyl Sepharose column chromatography | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-phenylalanine + tetrahydrobiopterin + O2 | - |
Homo sapiens | L-tyrosine + 4a-hydroxytetrahydrobiopterin | - |
? | |
L-phenylalanine + tetrahydrobiopterin + O2 | - |
Rattus norvegicus | L-tyrosine + 4a-hydroxytetrahydrobiopterin | - |
? |
Subunits | Comment | Organism |
---|---|---|
tetramer | 4 * 50000, SDS-PAGE | Homo sapiens |
tetramer | 4 * 50000, SDS-PAGE | Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
PAH | - |
Homo sapiens |
PAH | - |
Rattus norvegicus |
phenylalanine hydroxylase | - |
Homo sapiens |
phenylalanine hydroxylase | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
malfunction | phenylalanine hydroxylase dysfunction causes phenylketonuria | Homo sapiens |
malfunction | phenylalanine hydroxylase dysfunction causes phenylketonuria | Rattus norvegicus |