Crystallization (Comment) | Organism |
---|---|
in complex with 6(R)-L-erythro-5,6,7,8-tetrahydrobiopterin and substrate analogues 3-(2-thienyl)-L-alanine or L-norleucine | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P00439 | - |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
L-phenylalanine + a 5,6,7,8-tetrahydropteridine + O2 = L-tyrosine + a 4a-hydroxy-5,6,7,8-tetrahydropteridine | substrate binding triggers structural changes throughout the entire tetrameric enzyme | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-(2-thienyl)-L-alanine + tetrahydrobiopterin + O2 | - |
Homo sapiens | ? + dihydrobiopterin + H2O | - |
? | |
L-norleucine + tetrahydrobiopterin + O2 | 5% of the activity with 3-(2-thienyl)-L-alanine | Homo sapiens | ? + dihydrobiopterin + H2O | - |
? |