Protein Variants | Comment | Organism |
---|---|---|
additional information | N-terminal deletion of amino acid residues 1-116, kinetics, thermal stability, oligomerization profile similar to wild-type. N-terminal deletion of amino acid residues 1-116 plus mutation Y325F, 3fold reduction in kcat-value | Homo sapiens |
Y325A | no enzymic activity, aggregation of protein | Homo sapiens |
Y325F | kinetics, thermal stability, oligomerization profile similar to wild-type | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
additional information | self-hydroxylation mechanism at Phe325, dependent on iron at the active site | Homo sapiens |