Literature summary for 1.14.16.1 extracted from

Yamashita, M.; Minato, S.; Arai, M.; Kishida, Y.; Nagatsu, T.; Umezawa, H.
Purification of phenylalanine hydroxylase from human adult and foetal livers with a monoclonal antibody (1985), Biochem. Biophys. Res. Commun., 133, 202-207.

Search for more literature for 1.14.16.1

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
49000	-	x * 49000, adult liver enzyme, SDS-PAGE	Homo sapiens
49000	-	x * 52000 + x * 49000, fetal liver enzyme, SDS-PAGE	Homo sapiens
52000	-	x * 52000 + x * 49000, fetal liver enzyme, SDS-PAGE	Homo sapiens
150000	-	adult liver enzyme, gel filtration	Homo sapiens
160000	-	fetal liver enzyme, gel filtration	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
adult and fetal liver enzyme, monoclonal antibody affinity chromatography	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Homo sapiens	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
1.6	-	fetal liver enzyme	Homo sapiens
1.76	-	adult liver enzyme	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-phenylalanine + tetrahydrobiopterin + O2	-	Homo sapiens	L-tyrosine + dihydrobiopterin + H2O	-	?

Subunits

Subunits	Comment	Organism
?	x * 49000, adult liver enzyme, SDS-PAGE	Homo sapiens
?	x * 52000 + x * 49000, fetal liver enzyme, SDS-PAGE	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
tetrahydrobiopterin	-	Homo sapiens

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Release 2023.1 (January 2023)