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Literature summary for 1.14.15.6 extracted from

  • Rekawiecki, R.; Nomik, M.; Kotwica, J.
    Stimulatory effect of LH, PGE2 and progesterone on StAR protein, cytochrome P450 cholesterol side chain cleavage and 3beta hydroxysteroid dehydrogenase gene expression in bovine luteal cells (2005), Prostaglandins other Lipid Mediat., 78, 169-184.
    View publication on PubMed
Search for more literature for 1.14.15.6

Activating Compound

Activating Compound Comment Organism Structure
additional information luteinizing hormone, progesterone, and prostaglandin E2 induce enzyme expression in luteal cells Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
additional information S-nitroso-N-acetylpenicillamine inhibits enzyme transcription and translation in luteal cells Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cholesterol + reduced ferredoxin + O2 Bos taurus metabolic regulation of enzyme expression, overview pregnenolone + 4-methylpentanal + oxidized ferredoxin
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 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
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 female
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Source Tissue

Source Tissue Comment Organism Textmining
corpus luteum primary, from corpora lutea at day 6 to 10 of the estrous cycle, semi-quatitative enzyme expression analysis Bos taurus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cholesterol + reduced ferredoxin + O2
-
 Bos taurus pregnenolone + 4-methylpentanal + oxidized ferredoxin
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 ?
cholesterol + reduced ferredoxin + O2 metabolic regulation of enzyme expression, overview Bos taurus pregnenolone + 4-methylpentanal + oxidized ferredoxin
-
 ?

Synonyms

Synonyms Comment Organism
cytochrome P450 cholesterol side chain cleavage
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 Bos taurus
P450scc
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 Bos taurus

Cofactor

Cofactor Comment Organism Structure
Ferredoxin
-
 Bos taurus