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Literature summary for 1.14.15.5 extracted from

  • Sethupathi, V.; Vijayakumar, M.; Janakiraman, L.; Nammalwar, B.R.
    Congenital hypoaldosteronism (2008), Indian Pediatr., 45, 695-697.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
corticosterone + reduced adrenal ferredoxin + O2 Homo sapiens
-
18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O
-
?
additional information Homo sapiens reduced enzyme activity occurs in hyponatremia and hyperkalemia due to an isolated aldosterone biosynthesis defect, the phenotype can be rescued by a fludrocortisone replacement therapy, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
corticosterone + reduced adrenal ferredoxin + O2
-
Homo sapiens 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O
-
?
additional information reduced enzyme activity occurs in hyponatremia and hyperkalemia due to an isolated aldosterone biosynthesis defect, the phenotype can be rescued by a fludrocortisone replacement therapy, overview Homo sapiens ?
-
?