Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Streptomyces venezuelae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces venezuelae | O87605 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
10-deoxymethymycin + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 | i.e. YC-17 | Streptomyces venezuelae | methymycin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O | - |
? | |
10-deoxymethymycin + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 | - |
Streptomyces venezuelae | neomethymycin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O | - |
? | |
narbomycin + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 | - |
Streptomyces venezuelae | pikromycin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PikC | - |
Streptomyces venezuelae |
General Information | Comment | Organism |
---|---|---|
physiological function | inactivation of pikC gene abolishes production of all hydroxylated macrolides, with corresponding accumulation of 1-deoxymethymycin and narbomycin in the culture medium | Streptomyces venezuelae |