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Literature summary for 1.14.15.18 extracted from

  • Somjen, D.; Weisman, Y.; Kohen, F.; Gayer, B.; Limor, R.; Sharon, O.; Jaccard, N.; Knoll, E.; Stern, N.
    25-Hydroxyvitamin D3-1alpha-hydroxylase is expressed in human vascular smooth muscle cells and is upregulated by parathyroid hormone and estrogenic compounds (2005), Circulation, 111, 1666-1671.
    View publication on PubMed
Search for more literature for 1.14.15.18

Activating Compound

Activating Compound Comment Organism Structure
additional information treatment of cells with parathyroid hormone, estradiol-17beta, raloxifene, genistein, biochainin A, or 6-carboxy biochainin A increases cellular mRNA-level Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
25-hydroxyvitamin D3 + NADPH + O2 Homo sapiens final step of the activation of vitamin D 1alpha,25-dihydroxyvitamin D3 + NADP+ + H2O
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Homo sapiens
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vascular smooth muscle cell
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 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
25-hydroxyvitamin D3 + NADPH + O2
-
 Homo sapiens 1alpha,25-dihydroxyvitamin D3 + NADP+ + H2O
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 ?
25-hydroxyvitamin D3 + NADPH + O2 final step of the activation of vitamin D Homo sapiens 1alpha,25-dihydroxyvitamin D3 + NADP+ + H2O
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 ?

Synonyms

Synonyms Comment Organism
25-hydroxyvitamin D-1alpha-hydroxylase
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 Homo sapiens