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Literature summary for 1.14.15.18 extracted from

  • Botham, K.M.; Ghazarian, J.G.; Kream, B.E.; DeLuca, H.F.
    Isolation of an inhibitor of 25-hydroxyvitamin D3-1-hydroxylase from rat serum (1976), Biochemistry, 15, 2130-2135.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Natural inhibitors from rat serum Gallus gallus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Gallus gallus 5739
-

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
calcidiol + NADPH + O2 highly specific for calcidiol, calcidiol is identical with 25-hydroxycholecalciferol Gallus gallus calcitriol + NADP+ + H2O calcitriol is identical with 1,25-dihydroxycholecalciferol ?

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Gallus gallus