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Literature summary for 1.14.15.16 extracted from
- Metabolism of vitamin D3 by cytochromes P450 (2005), Front. Biosci., 10, 119-134.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli | Homo sapiens |
| expressed in Escherichia coli | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1alpha,25-dihydroxyvitamin D3 + NADPH + H+ + O2 | - |
Rattus norvegicus | calcitroic acid + NADP+ + ? | - |
? |  |
| 25-hydroxyvitamin D3 + NADPH + H+ + O2 | C-23 hydroxylation | Homo sapiens | 1alpha,25-dihydroxyvitamin D3-26,23-lactone + NADP+ + H2O | - |
? | |
| 25-hydroxyvitamin D3 + NADPH + H+ + O2 | C-24 hydroxylation | Homo sapiens | 24R,25-dihydroxyvitamin D3 + NADP+ + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 1alpha,25-dihydroxyvitamin D3 24-hydroxylase | - |
Homo sapiens |
| 1alpha,25-dihydroxyvitamin D3 24-hydroxylase | - |
Rattus norvegicus |
| CYP24A1 | - |
Homo sapiens |
| CYP24A1 | - |
Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Homo sapiens | |
| NADPH | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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