Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli JM109 cells | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1alpha,25-dihydroxyvitamin D3 + NADPH + H+ + O2 | after hydrogen abstraction of the C-23 position of 1alpha,25-dihydroxyvitamin D3, part of the substrate-radical intermediate is converted into 25,26,27-trinor-23-ene-1alpha-hydroxyvitamin D3, while a major part of them is converted into 1alpha,23,25-trihydroxyvitamin D3 | Homo sapiens | 1alpha,23,25-trihydroxyvitamin D3 + 25,26,27-trinor-23-ene-1alpha-hydroxyvitamin D3 + NADP+ + H2O | - |
? | |
25-hydroxyvitamin D3 + NADPH + H+ + O2 | - |
Homo sapiens | 25,26,27-trinor-23-ene-vitamin D3 + NADP+ + H2O | the metabolite 25,26,27-trinor-23-ene-vitamin D3 is closely related with the C-23 hydroxylation pathway | ? |
Synonyms | Comment | Organism |
---|---|---|
CYP24A1 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | - |
Homo sapiens | |
NADPH | - |
Homo sapiens |