Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-nicotine + [reduced NADPH-hemoprotein reductase] + O2 | Nicotiana tabacum | CYP82E4 selectively demethylates (S)-nicotine | (S)-nornicotine + formaldehyde + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Nicotiana tabacum | - |
cultivar TN 90LC | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leaf | - |
Nicotiana tabacum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-nicotine + [reduced NADPH-hemoprotein reductase] + O2 | CYP82E4 selectively demethylates (S)-nicotine | Nicotiana tabacum | (S)-nornicotine + formaldehyde + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CYP82E4 | - |
Nicotiana tabacum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Nicotiana tabacum |