BRENDA - Enzyme Database
show all sequences of 1.14.14.B10

Escherichia coli heme oxygenase modulates host innate immune responses

Maharshak, N.; Ryu, H.S.; Fan, T.J.; Onyiah, J.C.; Schulz, S.; Otterbein, S.L.; Wong, R.; Hansen, J.J.; Otterbein, L.E.; Carroll, I.M.; Plevy, S.E.; Microbiol. Immunol. 59, 452-465 (2015)

Data extracted from this reference:

Organism
Organism
UniProt
Commentary
Textmining
Escherichia coli
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Escherichia coli NC101
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Synonyms
Synonyms
Commentary
Organism
ChuS
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Escherichia coli
Expression
Organism
Commentary
Expression
Escherichia coli
incubation of strain NC101 with an iron chelator results in more than 300fold increase in ChuS mRNA expression
up
General Information
General Information
Commentary
Organism
physiological function
coculture of ChuS-overexpressing Escherichia coli with bone marrow derived macrophages results in decreased IL-12 p40 and increased IL-10 secretion compared to wild-type or ChuS-deficient Escherichia coli. Mice infected with ChuS-overexpressing Escherichia coli have increased levels of hepatic carbon monoxide and decreased serum IL-12 p40
Escherichia coli
General Information (protein specific)
General Information
Commentary
Organism
physiological function
coculture of ChuS-overexpressing Escherichia coli with bone marrow derived macrophages results in decreased IL-12 p40 and increased IL-10 secretion compared to wild-type or ChuS-deficient Escherichia coli. Mice infected with ChuS-overexpressing Escherichia coli have increased levels of hepatic carbon monoxide and decreased serum IL-12 p40
Escherichia coli
Expression (protein specific)
Organism
Commentary
Expression
Escherichia coli
incubation of strain NC101 with an iron chelator results in more than 300fold increase in ChuS mRNA expression
up
Other publictions for EC 1.14.14.B10
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
745504
Ouellet
An alternative reaction for h ...
Escherichia coli
J. Inorg. Biochem.
154
103-113
2016
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745713
Maharshak
Escherichia coli heme oxygena ...
Escherichia coli, Escherichia coli NC101
Microbiol. Immunol.
59
452-465
2015
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