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Literature summary for 1.14.14.B10 extracted from

  • Maharshak, N.; Ryu, H.S.; Fan, T.J.; Onyiah, J.C.; Schulz, S.; Otterbein, S.L.; Wong, R.; Hansen, J.J.; Otterbein, L.E.; Carroll, I.M.; Plevy, S.E.
    Escherichia coli heme oxygenase modulates host innate immune responses (2015), Microbiol. Immunol., 59, 452-465 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Escherichia coli
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-
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Escherichia coli NC101
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Synonyms

Synonyms Comment Organism
ChuS
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Escherichia coli

Expression

Organism Comment Expression
Escherichia coli incubation of strain NC101 with an iron chelator results in more than 300fold increase in ChuS mRNA expression up

General Information

General Information Comment Organism
physiological function coculture of ChuS-overexpressing Escherichia coli with bone marrow derived macrophages results in decreased IL-12 p40 and increased IL-10 secretion compared to wild-type or ChuS-deficient Escherichia coli. Mice infected with ChuS-overexpressing Escherichia coli have increased levels of hepatic carbon monoxide and decreased serum IL-12 p40 Escherichia coli