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Literature summary for 1.14.14.90 extracted from

  • Akashi, T.; Aoki, T.; Ayabe, S.I.
    CYP81E1, a cytochrome P450 cDNA of licorice (Glycyrrhiza echinata L.), encodes isoflavone 2'-hydroxylase (1998), Biochem. Biophys. Res. Commun., 251, 67-70.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Saccharomyces cerevisiae Glycyrrhiza echinata

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Glycyrrhiza echinata the enzyme is involved in the biosynthesis of isoflavonoid-derived antimicrobial compounds of legumes ?
-
?
additional information Glycyrrhiza echinata L. the enzyme is involved in the biosynthesis of isoflavonoid-derived antimicrobial compounds of legumes ?
-
?

Organism

Organism UniProt Comment Textmining
Glycyrrhiza echinata P93147 L.
-
Glycyrrhiza echinata L. P93147 L.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
daidzein + [reduced NADPH-hemoprotein reductase] + O2
-
Glycyrrhiza echinata 2'-hydroxydaidzein + [oxidized NADPH-hemoprotein reductase] + H2O
-
?
daidzein + [reduced NADPH-hemoprotein reductase] + O2
-
Glycyrrhiza echinata L. 2'-hydroxydaidzein + [oxidized NADPH-hemoprotein reductase] + H2O
-
?
formononetin + [reduced NADPH-hemoprotein reductase] + O2
-
Glycyrrhiza echinata 2'-hydroxyformononetin + [oxidized NADPH-hemoprotein reductase] + H2O
-
?
formononetin + [reduced NADPH-hemoprotein reductase] + O2
-
Glycyrrhiza echinata L. 2'-hydroxyformononetin + [oxidized NADPH-hemoprotein reductase] + H2O
-
?
genistein + [reduced NADPH-hemoprotein reductase] + O2
-
Glycyrrhiza echinata 2'-hydroxygenistein + [oxidized NADPH-hemoprotein reductase] + H2O
-
?
genistein + [reduced NADPH-hemoprotein reductase] + O2
-
Glycyrrhiza echinata L. 2'-hydroxygenistein + [oxidized NADPH-hemoprotein reductase] + H2O
-
?
additional information the enzyme is involved in the biosynthesis of isoflavonoid-derived antimicrobial compounds of legumes Glycyrrhiza echinata ?
-
?
additional information no activity with naringenin (5,7,4'-trihydroxyflavanone), liquiritigenin (7,4'-dihydroxyflavanone), trans-cinnamic acid and 4-coumaric acid Glycyrrhiza echinata ?
-
?
additional information the enzyme is involved in the biosynthesis of isoflavonoid-derived antimicrobial compounds of legumes Glycyrrhiza echinata L. ?
-
?
additional information no activity with naringenin (5,7,4'-trihydroxyflavanone), liquiritigenin (7,4'-dihydroxyflavanone), trans-cinnamic acid and 4-coumaric acid Glycyrrhiza echinata L. ?
-
?

Synonyms

Synonyms Comment Organism
CYP Ge-3
-
Glycyrrhiza echinata
CYP81E1
-
Glycyrrhiza echinata
isoflavone 2'-monooxygenase
-
Glycyrrhiza echinata

Cofactor

Cofactor Comment Organism Structure
cytochrome P450
-
Glycyrrhiza echinata