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Literature summary for 1.14.14.87 extracted from
- Reaction mechanism of oxidative rearrangement of flavanone in isoflavone biosynthesis (1990), FEBS Lett., 271, 219-22.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ancymidol | complete inhibition at 1 mM | Pueraria montana var. lobata |  |
| CO2 | 52% inhibition in the presence of CO2 gas | Pueraria montana var. lobata | |
| Metyrapone | complete inhibition at 0.1 mM | Pueraria montana var. lobata | |
| SKF 525-A | 73% inhibition at 2 mM | Pueraria montana var. lobata | |
| uniconazole | complete inhibition at 0.1 mM | Pueraria montana var. lobata | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Pueraria montana var. lobata | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Iron | the (P450) enzyme contains iron | Pueraria montana var. lobata | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pueraria montana var. lobata | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| liquiritigenin + [reduced NADPH-hemoprotein reductase] + O2 | - |
Pueraria montana var. lobata | 2,7,4'-trihydroxyisoflavanone + [oxidized NADPH-hemoprotein reductase] + H2O | major product is 2,7,4'-trihydroxyisoflavanone which further reacts to daidzein | ? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CYT93C | - |
Pueraria montana var. lobata |
| IFS | - |
Pueraria montana var. lobata |
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Release 2023.1 (January 2023)
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