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Literature summary for 1.14.14.81 extracted from

  • Hammerbacher, A.; Raguschke, B.; Wright, L.; Gershenzon, J.
    Gallocatechin biosynthesis via a flavonoid 3',5'-hydroxylase is a defense response in Norway spruce against infection by the bark beetle-associated sap-staining fungus Endoconidiophora polonica (2018), Phytochemistry, 148, 78-86 .
No PubMed abstract available
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2,3-(trans)-(+)-catechin + [reduced NADPH-hemoprotein reductase] + O2 Picea abies
-
 2,3-(trans)-(+)-gallocatechin + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
dihydroquercetin + [reduced NADPH-hemoprotein reductase] + O2 Picea abies
-
 dihydromyricetin + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
leucocyanidin + [reduced NADPH-hemoprotein reductase] + O2 Picea abies
-
 leucodelphinidin + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Picea abies
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,3-(trans)-(+)-catechin + [reduced NADPH-hemoprotein reductase] + O2
-
 Picea abies 2,3-(trans)-(+)-gallocatechin + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
dihydroquercetin + [reduced NADPH-hemoprotein reductase] + O2
-
 Picea abies dihydromyricetin + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
leucocyanidin + [reduced NADPH-hemoprotein reductase] + O2
-
 Picea abies leucodelphinidin + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

Synonyms Comment Organism
CYP75A42
-
 Picea abies

Expression

Organism Comment Expression
Picea abies transcript abundance of the flavonoid 3',5'-hydroxylase gene increases significantly during infection with fungus Endoconidiophora polonica up

General Information

General Information Comment Organism
physiological function coexpression with Norway spruce and apple genes encoding the rest of the flavonoid pathway, PaCHS, PaF3H, PaF30H, MdDFR and PaLAR3, in Nicotiana benthamiana leaves. Catechin and 2,3-(trans)-(+)-gallocatechin accumulate in the leaves 7 days after Agrobacterium infiltration. There is a significant increase in the gallocatechin content of Norway spruce bark and wood after inoculation with the bark beetle-associated sap-staining fungus Endoconidiophora polonica. 2,3 (trans)-(+)-catechin is a stronger inhibitor of fungal growth, while 2,3 (trans)-(+)-gallocatechin is a stronger inhibitor of melanin biosynthesis Picea abies