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Literature summary for 1.14.14.81 extracted from

  • Katsumoto, Y.; Fukuchi-Mizutani, M.; Fukui, Y.; Brugliera, F.; Holton, T.A.; Karan, M.; Nakamura, N.; Yonekura-Sakakibara, K.; Togami, J.; Pigeaire, A.; Tao, G.Q.; Nehra, N.S.; Lu, C.Y.; Dyson, B.K.; Tsuda, S.; Ashikari, T.; Kusumi, T.; Mason, J.G.; Tanaka, Y.
    Engineering of the rose flavonoid biosynthetic pathway successfully generated blue-hued flowers accumulating delphinidin (2007), Plant Cell Physiol., 48, 1589-1600.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expression in Rosa hybrida transgenic plants, the mutant plants show the accumulation of a high percentage of delphinidin in selected cultuvars, while the wild-type lacks delphinidin and derivatives and the activity of F3'5'H Viola sp.

Protein Variants

Protein Variants Comment Organism
additional information establishment of a bluish color, achieved by delphinidin and derivatives, in Rosa hybrida by overexpression of the F3'5'H gene from Viola sp. and the dihydroflavonol 4-reductase gene from Iris hollandica, while the endogenous dihydroflavonol 4-reductase gene is downregulated, the ability for exclusive accumulation of delphinidin is inherited by the next generations, phenotype, overview Viola sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dihydrokaempferol + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 Viola sp. leads to synthesis of delphinidin dihydromyricetin + 2 [oxidized NADPH-hemoprotein reductase] + 2 H2O
-
 ?

Organism

Organism UniProt Comment Textmining
no activity in Rosa hybrida
-
-
-
Viola sp.
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
flower
-
 Viola sp.
-
petal
-
 Viola sp.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dihydrokaempferol + 2 [reduced NADPH-hemoprotein reductase] + 2 O2
-
 Viola sp. dihydromyricetin + 2 [oxidized NADPH-hemoprotein reductase] + 2 H2O
-
 ?
dihydrokaempferol + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 leads to synthesis of delphinidin Viola sp. dihydromyricetin + 2 [oxidized NADPH-hemoprotein reductase] + 2 H2O
-
 ?

Synonyms

Synonyms Comment Organism
F3'5'H
-
 Viola sp.