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Literature summary for 1.14.14.55 extracted from

  • Relling, M.V.; Evans, R.; Dass, C.; Desiderio, D.M.; Nemec, J.
    Human cytochrome P450 metabolism of teniposide and etoposide (1992), J. Pharmacol. Exp. Ther., 261, 491-496.
    View publication on PubMed
Search for more literature for 1.14.14.55

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 tenoposide between 0.0197 mM and 0.0435 mM Homo sapiens
additional information
-
 etoposide between 0.0421 mM and 0.1151 mM Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 human
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
etoposide + NADPH + O2
-
 Homo sapiens 3'-demethyletoposide + NADP+ + H2O
-
 ?
teniposide + [reduced NADPH-hemoprotein reductase] + O2
-
 Homo sapiens teniposide catechol + [oxidized NADPH-hemoprotein reductase] + ?
-
 ?