Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Bacillus subtilis |
Crystallization (Comment) | Organism |
---|---|
wild-tye and mutant I208V, in complex with inhibitors | Bacillus subtilis |
Protein Variants | Comment | Organism |
---|---|---|
I208V | crystallization and inhibition data | Bacillus subtilis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-methylquinolin-2-amine | among the most potent aminoquinoline inhibitors tested, KS value 0.00080 mM | Bacillus subtilis | |
quinolin-2-amine | among the most potent aminoquinoline inhibitors tested, KS value 0.00125 mM | Bacillus subtilis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus subtilis | O34453 | - |
- |
Bacillus subtilis 168 | O34453 | - |
- |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0273 | - |
wild-type, pH not specified in the publication, temperature not specified in the publication | Bacillus subtilis | quinolin-2-amine | |
0.0366 | - |
wild-type, pH not specified in the publication, temperature not specified in the publication | Bacillus subtilis | 4-methylquinolin-2-amine | |
0.0533 | - |
mutant I208V, pH not specified in the publication, temperature not specified in the publication | Bacillus subtilis | 4-methylquinolin-2-amine | |
0.0639 | - |
mutant I208V, pH not specified in the publication, temperature not specified in the publication | Bacillus subtilis | quinolin-2-amine |