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Literature summary for 1.14.14.35 extracted from

  • Endoh, T.; Habe, H.; Nojiri, H.; Yamane, H.; Omori, T.
    The sigma54-dependent transcriptional activator SfnR regulates the expression of the Pseudomonas putida sfnFG operon responsible for dimethyl sulphone utilization (2005), Mol. Microbiol., 55, 897-911.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Pseudomonas putida

Organism

Organism UniProt Comment Textmining
Pseudomonas putida Q65YW9
-
-
Pseudomonas putida DS1 Q65YW9
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dimethyl sulfone + FMNH2 + O2
-
Pseudomonas putida methanesulfinate + formaldehyde + FMN + H2O
-
?
dimethyl sulfone + FMNH2 + O2
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Pseudomonas putida DS1 methanesulfinate + formaldehyde + FMN + H2O
-
?

Synonyms

Synonyms Comment Organism
sfnG
-
Pseudomonas putida

Expression

Organism Comment Expression
Pseudomonas putida expression of the sfnFG operon is directly activated by the binding of sigma54-dependent transcriptional activator SfnR at its upstream region additional information

General Information

General Information Comment Organism
physiological function the sfnG product is essential for dimethyl sulfone utilization by Pseudomonas putida DS1. SfnG is an FMNH2-dependent DMSO2 monooxygenase that converts DMSO2 to methanesulfinate. A SfnG mutant is still able to utilize methionine sulfone as a sulfur source Pseudomonas putida