Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-(1H-imidazol-1-ylmethyl)phenyl 4-(trifluoromethyl)benzenesulfonate | - |
Rattus norvegicus | |
4-(1H-imidazol-1-ylmethyl)phenyl 4-bromobenzenesulfonate | - |
Rattus norvegicus | |
4-(1H-imidazol-1-ylmethyl)phenyl 4-chlorobenzenesulfonate | - |
Rattus norvegicus | |
4-(1H-imidazol-1-ylmethyl)phenyl 4-fluorobenzenesulfonate | - |
Rattus norvegicus | |
4-(1H-imidazol-1-ylmethyl)phenyl 4-iodobenzenesulfonate | - |
Rattus norvegicus | |
4-(1H-imidazol-1-ylmethyl)phenyl 4-methoxybenzenesulfonate | - |
Rattus norvegicus | |
4-(1H-imidazol-1-ylmethyl)phenyl 4-nitrobenzenesulfonate | - |
Rattus norvegicus | |
4-(1H-imidazol-1-ylmethylphenyl)-4-toluenesulfonate | - |
Rattus norvegicus | |
4-iodobenzyl imidazole | - |
Rattus norvegicus | |
ketoconazole | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
testis | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2 | - |
Rattus norvegicus | androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
17,20 lyase | - |
Rattus norvegicus |
17alpha-hydroxylase/17,20-lyase | - |
Rattus norvegicus |
P-45017alpha | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0000651 | - |
at 37°C | Rattus norvegicus | 4-(1H-imidazol-1-ylmethyl)phenyl 4-iodobenzenesulfonate | |
0.0000704 | - |
at 37°C | Rattus norvegicus | 4-(1H-imidazol-1-ylmethyl)phenyl 4-bromobenzenesulfonate | |
0.000085 | - |
at 37°C | Rattus norvegicus | 4-(1H-imidazol-1-ylmethyl)phenyl 4-nitrobenzenesulfonate | |
0.0000987 | - |
at 37°C | Rattus norvegicus | 4-(1H-imidazol-1-ylmethyl)phenyl 4-chlorobenzenesulfonate | |
0.0001009 | - |
at 37°C | Rattus norvegicus | 4-(1H-imidazol-1-ylmethyl)phenyl 4-methoxybenzenesulfonate | |
0.00021 | - |
at 37°C | Rattus norvegicus | 4-(1H-imidazol-1-ylmethyl)phenyl 4-fluorobenzenesulfonate | |
0.00023 | - |
at 37°C | Rattus norvegicus | 4-(1H-imidazol-1-ylmethylphenyl)-4-toluenesulfonate | |
0.0002908 | - |
at 37°C | Rattus norvegicus | 4-(1H-imidazol-1-ylmethyl)phenyl 4-(trifluoromethyl)benzenesulfonate | |
0.00158 | - |
at 37°C | Rattus norvegicus | 4-iodobenzyl imidazole | |
0.00166 | - |
at 37°C | Rattus norvegicus | ketoconazole |