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Literature summary for 1.14.14.29 extracted from

  • Hennebert, O.; Chalbot, S.; Alran, S.; Morfin, R.
    Dehydroepiandrosterone 7alpha-hydroxylation in human tissues: possible interference with type 1 11beta-hydroxysteroid dehydrogenase-mediated processes (2007), J. Steroid Biochem. Mol. Biol., 104, 326-333.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte
-
Homo sapiens
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liver
-
Homo sapiens
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skin activity is detected in keratinocytes of the spinous and granula layers, and to lesser extent in the basal layer and basal cell bodies. High activity in hair follicle associated cells Homo sapiens
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tonsil CYP7B1 occurrs in trabecular stroma cells Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dehydroepiandrosterone + NADPH + H+ + o2
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Homo sapiens 7alpha-hydroxy-dehydroepiandrosterone + NADP+ + H2O
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?

Synonyms

Synonyms Comment Organism
CYP7B1
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Homo sapiens
cytochome P450 7B1
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Homo sapiens