Literature summary for 1.14.14.19 extracted from

Hartmann, R.W.; Ehmer, P.B.; Haidar, S.; Hector, M.; Jose, J.; Klein, C.D.; Seidel, S.B.; Sergejew, T.F.; Wachall, B.G.; Wachter, G.A.; Zhuang, Y.
Inhibition of CYP 17, a new strategy for the treatment of prostata cancer (2002), Arch. Pharm., 335, 119-128.

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Application

Application	Comment	Organism
medicine	inhibition of steroid 17alpha-monooxygenase is an important therapeutic strategy in order to inhibit tumor growth in prostate cancer	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	catalyzes the last step of androgen biosynthesis in both testes and adrenals	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	catalyzes the last step of androgen biosynthesis in both testes and adrenals	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)